Research Topic: Functional genomics of immune cells

Giving Immunotherapy Cells Resilience to Pass the ‘Stress Test’

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

CRISPR activation and interference screens decode stimulation responses in primary human T cells

Gene Editing Expands to New Types of Immune Cells

Genetic Network that Differentiates Regulatory T Cells Mapped

Scientists map genes controlling immune system “brakes”

Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

CRISPR screen in regulatory T cells reveals modulators of Foxp3

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function