A functional map of HIV-host interactions in primary human T cells

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CRISPR-Cas9 genome engineering of primary CD4 + T cells for the interrogation of HIV-host factor interactions

Genetics Of The Host-Pathogen Interface

A variety of research projects in the lab focus on the application of genomic technology to host-pathogen interactions, with the broad goal of understanding pathogenesis and advancing therapies. Projects include the development of a systematic approach to identify gene targets that render human T cells resistant to HIV infection and extension of these efforts to […]

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells